Voltaren® Gel works right at the site of the pain for direct OA joint pain relief
Compared to 100% of the equivalent oral medication, only 6% of the active ingredient in Voltaren Gel is absorbed throughout the entire body†
Every time you massage in Voltaren Gel, it works right at the site of pain to provide effective relief. And because of how it is formulated, only 6% of the active ingredient in Voltaren Gel is absorbed throughout the entire body compared to 100% of the equivalent oral dose.
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With Voltaren Gel, you can target the pain relief in areas where it is most needed with lower exposure to the rest of the body.
†6% of the active ingredient in Voltaren Gel is absorbed throughout the body when the recommended dose of 4 g of Voltaren Gel is applied to 1 knee 4 times a day, compared to an oral dose of 50 mg taken 3 times a day.
20% of the active ingredient in Voltaren Gel is absorbed throughout the body when a dose of 12 g of
Voltaren Gel is applied to 2 knees and 2 hands 4 times a day, compared to an oral dose of 50 mg taken 3 times a day; 12 g taken 4 times a day is not an approved dose.
For U.S. Only
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Important Safety Information
*Voltaren® Gel is indicated for the relief of the pain of osteoarthritis of joints amenable to topical treatment, such as the knees and those of the hands. Voltaren Gel has not been evaluated for use on the spine, hip, or shoulder.
Cardiovascular Risk
- Nonsteroidal anti-inflammatory drugs (NSAIDs) may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk [see Warnings and Precautions].
- Voltaren Gel is contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery [see Contraindications].
Gastrointestinal Risk
- NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events [see Warnings and Precautions].
The most common adverse reactions reported in Voltaren Gel clinical trials were application site reactions in 7% of treated patients. With all NSAIDs there may be an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.
The use of Voltaren Gel is contraindicated in patients with a known hypersensitivity to diclofenac.
Voltaren Gel should not be administered in patients who have experienced asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients.
Voltaren Gel should not be used in combination with other oral NSAIDs or aspirin because of the potential for increased adverse effects. Similarly, combined use of Voltaren Gel with other topical products, such as sunscreens and cosmetics, on the same skin area has not been tested and should be avoided because of the potential to alter local tolerability and absorption.
There is a potential for elevation in liver function tests during treatment with diclofenac containing products.
Safety and effectiveness in pediatric patients have not been established.
Please see full Prescribing Information for Warnings and Contraindications.
